Reciprocating Cylinder Apparatus
The Reciprocating Cylinder Apparatus is ideal for automatic dissolution testing of dosage forms that require different types of media. Reciprocating Cylinder Apparatus is typically used for imitating the pH changes that occur in the body and is perfectly suited for extended and sustained release dosage forms. The Reciprocating Cylinder Apparatus can automatically transport samples to another row of media, simulating the gastrointestinal changes that occur in vivo. Capable of running unattended for periods of up to six days, the store up to 15 programs and provide direct control over timepoints, agitation rate, sampling rate, movement between vessel rows, hold dip time, and drain time. The Reciprocating Cylinder Apparatus is designed to meet current USP Apparatus 3 and EP Reciprocating Cylinder Apparatus.
Features of Reciprocating Cylinder Apparatus
- Biorelevant - Simulate gastrointestinal conditions with simple programming that allows in vitro dissolution pH profiling with biorelevant agitation rates and retention times.
- Flexible - useful for release-rate testing of floating dosage forms, beads and chewables. Use one instrument to test and transport a variety of samples, saving valuable bench space. Samples are automatically transported from one medium to the next without operator intervention.
- Compliant - be confident knowing the compliant with the reciprocating cylinder apparatus, USP Apparatus 3 and EP harmonized specifications.
- Easily configured - select a standard volumetric reciprocating cylinder option or small and large volume configuration to meet testing needs for low dose or poorly soluble formulations. Other options include a double row instrument for increased testing throughput.
- Automated Sampling - easily perform automated sampling by integrating the Dissolution Sampling Station.
- Reporting - the built-in Report Center Printer provides hard-copy documentation of testing progress and conditions. A four-line digital display provides updated operation information as the test progresses.